Written by Dr. Juan Carlos Cassano
LinkedIn Profile: Juan Carlos Cassano
Key Takeaway
The best fertility boosters include folate, vitamin D, CoQ10, omega-3s, zinc, inositol, and antioxidants like vitamins C and E. These nutrients support egg and sperm quality, hormone balance, ovulation, and embryo development. Organ-based supplements may help by providing them in bioavailable, natural forms.
In today’s industrialized and fast-paced world, fertility is facing unprecedented challenges. While technology has made life more convenient and efficient, it has also introduced a host of environmental and lifestyle factors that impair reproductive health.
The average sperm count in men has dropped by more than 50% since the middle of the 20th century, and testosterone levels have declined by 1% per year since the 1980s, according to global meta-analyses and longitudinal studies (Carlson et al 1992; Levine et al., 2017, Travison et al., 2007).
In women, rising rates of obesity, endocrine-disrupting chemicals (found in plastics, pesticides, and cosmetics), and the trend of delaying childbirth until later in life are also major contributing factors to female infertility.
Research has shown that obesity alone can reduce a woman’s chances of getting pregnant by up to 50%, while compounds like parabens and phthalates, commonly used in personal care products, act as xenoestrogens, mimicking estrogen and disrupting hormonal balance (Chavarro et al., 2007, Patisaul & Adewale, 2009).
Furthermore, chronic stress, irregular sleep, nutrient-poor diets and an increase in processed foods contribute to hormonal imbalances, oxidative stress, and mitochondrial dysfunction, undermining the body’s ability to reproduce naturally.
Against this backdrop, targeted nutritional supplementation has emerged as an essential and proactive step in restoring reproductive health.
Why Nutrients Matter for Reproductive Health
While no supplement can replace the fundamentals of sleep, managing stress, whole-food nutrition, and maintaining a healthy weight, lifestyle choices like eating a balanced diet, engaging in moderate physical activity, and consuming enough dietary fiber also play key roles in reproductive wellbeing.
In addition to these habits, targeted compounds like folic acid, vitamin D, CoQ10, and omega-3s, along with nutrient-dense organ extracts, can help replenish essential nutrients, restore hormonal balance, and optimize egg cells, sperm, and embryo quality.
This holistic approach is not merely about enhancing fertility outcomes; it’s about empowering couples to pursue a healthy pregnancy in an environment that increasingly works against it.
Restoring and enhancing fertility, whether male or female, often involves addressing nutritional, metabolic, and oxidative stress factors. Scientific evidence identifies several supplements that support reproductive health: folic acid, vitamin D, CoQ10, omega-3 fatty acids, along with helpful adjuncts like vitamin C, vitamin E, zinc, and inositol.
Nutriest offers unique whole-food organ-based products, such as Beef Testicle, Pregnancy & Fertility, Beef Liver, and Beef Blood, that complement these supplements by providing nutrients in their natural, synergistic form. Below is an evidence-based look at these nutrients, how they can affect fertility, and where Nutriest’s organ extracts fit in.
Top Supplements for Fertility Support
1. Folic Acid (Vitamin B₉)
Folate is critical in DNA synthesis, amino acid metabolism, and embryonic neural tube development. Preconception folic acid supplementation significantly reduces the risk of neural tube defects, with recommendations of 0.4–0.8 mg daily, especially in the months before and during early pregnancy (Greenberg et al 2011, Kadir et al 2023).
Further evidence shows folate impacts broader fertility outcomes. For example, sufficient folate reduces homocysteine levels, linked to preeclampsia risk, and supports oocyte quality and implantation (D’Angelo 2002, Kaldygulova et al 2023).
For men, folic acid combined with zinc has been shown to improve sperm health and morphology, enhancing conception potential.
Nutriest Synergy: Fortunately, Nutriest’s Pregnancy & Fertility product and Beef Liver supplements provide bioavailable folate (5-methyl-THF) and cofactors essential for methylation pathways, supporting both male and female fertility naturally.
2. Vitamin D
Vitamin D receptors are located in reproductive tissues across both sexes. Deficiency correlates with lower IVF success, poor semen quality, and increased risk of pregnancy complications. Supplementation (~1,000 IU/day) in infertile women has demonstrated improved pregnancy outcomes (Lerchbaum 2012, Xu 2017).
Nutriest Synergy: While some Vitamin D comes from sun exposure, Nutriest’s whole-food extracts—especially Beef Liver and Beef Blood—also provide small amounts of vitamin D alongside essential fat-soluble nutrients, enhancing uptake and utilization.
3. Coenzyme Q₁₀ (CoQ10)
CoQ10 is a mitochondrial antioxidant critical for gamete quality. Meta-analyses show that CoQ10 supplementation doubles clinical pregnancy rates in women undergoing ART (28.8% vs. 14.1%), though live birth rates were not yet significantly improved (Florou et al 2020)
In men, higher CoQ10 correlates with increased sperm count, motility, and morphology, key sperm quality markers (Bentov 2023, Alahmar et al 2021).
Nutriest Synergy: Beef Heart is a rich source of CoQ10, and combining CoQ10 rich-Beef Heart with Beef Testicle or Beef Liver may enhance energy metabolism and hormone balance.
4. Omega-3 Fatty Acids (EPA/DHA)
Rich in EPA and DHA, omega-3s support embryo implantation, prevent preterm birth, and improve sperm quality (Safarinejad 2011, Jensen et al 2019, Trop-Steinberg et al 2024).
– Observational data link fish oil with higher semen quality and conception rates. – DHA/EPA support uterine receptivity and placental function during pregnancy.
Nutriest Synergy: Beef Blood and Liver contain PUFAs and phospholipids that support systemic inflammation balance and fatty acid status—an essential component of fertility health.
5. Vitamin C & Vitamin E
Both are potent antioxidants that mitigate oxidative stress, common in sperm and oocyte aging (Esmaeilzadeh 2013, Gulbayek 2022).
Evidence shows vitamin C and E supplementation improves seminal antioxidant capacity and sperm motility, particularly in combination with other micronutrients (Dimitriadis 2023).
Nutriest Synergy: Nutriest organ extracts contain natural forms of vitamin E (in fat-soluble complexes), vitamin C cofactors, and trace minerals that bolster antioxidant defenses.
6. Zinc
Zinc is essential for sperm chromatin formation, testosterone metabolism, and ovarian function. Men with zinc supplementation exhibit improved sperm quality and sexual health (Agarwal 2021). It is particularly helpful for men with iron deficiency or low libido.
Zinc deficiency impairs female fertility via disrupted ovarian function.
Nutriest Synergy: Beef Testicle and Beef Liver offer naturally high zinc concentrations in bioavailable forms that support enzymatic functions in reproduction.
7. Inositol
Myoinositol and D-chiro-inositol are important for insulin signaling, oocyte maturation, and PCOS-related fertility improvements (Nestler 1999). A 2017 meta-analysis showed that myoinositol significantly improved ovulation and pregnancy rates in PCOS patients (Unfer 2017).
Nutriest Synergy: While inositol isn’t directly included in organ extracts, the Pregnancy & Fertility formulation may offer cofactors that enhance cellular signaling and metabolic response. These nutrients play a role in hormonal balance and ovulatory function, which are key to boosting fertility and supporting efforts to get pregnant naturally.
8. Whole-Food Organ Supplements: Nutriest’s Edge
Rather than single nutrient pills, Nutriest delivers complex, evolutionarily-recognized nutrients via freeze-dried organ extracts:
- Beef Testicle: Rich in activin, inhibin, EGF, cholesterol, zinc—supports spermatogenesis and testosterone balance.
- Pregnancy & Fertility: Blends liver, testicle, and blood to support healthy pregnancy and conception
- Beef Liver: High in bioavailable vitamin A, folate, B12, and iron—supports oocyte quality, sperm metabolism, and hematologic support for pregnant women.
- Beef Blood: Delivers heme iron and fatty acids for blood circulation, oxygenation, and energy production
Supplementation Recommendations
| Supplement | Men’s Dose | Women’s Dose | Purpose |
| Folic acid (or 5-MTHF) | 400–800 µg | 400–800 µg preconception & pregnancy | DNA, oocyte/sperm quality, neural protection |
| Vitamin D | 1,000–2,000 IU | Same | Semen motility, uterine receptivity, pregnancy outcomes |
| CoQ10 | 200–600 mg | 200–600 mg | Egg/sperm mitochondrial function |
| Omega-3 (EPA+DHA) | 1–2 g | Same | Sperm quality, embryo/placenta health |
| Vitamin C/E combo | 500–1000 mg C + 200–400 IU E | Same | Antioxidant protection for gametes |
| Zinc | 15–30 mg | 8–12 mg | Hormone balance, semen quality, ovarian function |
| Inositol | 2–4 g | 2–4 g (PCOS/ovulation) | Regulate menstrual cycles, support oocyte health, insulin sensitivity. |
Always check with your healthcare provider before starting new supplements, especially if you are undergoing fertility treatments or managing other conditions like autoimmune diseases.
Integrating Nutriest Organ Extracts
Daily protocol example:
- Beef Testicle: 2–4 caps (men) with meals
- Pregnancy & Fertility: 3–4 caps (women) daily
- Beef Liver/Blood: 2 caps daily for all
- Pair with therapeutic supplements (CoQ10, omega-3, etc.) as needed
Clinical-lab monitoring ensures no nutrient excess and tracks clinical benefits.
Quality and Safety: Nutriest Standards
- Grass-fed cattle, hormone/antibiotic-free
- Freeze-dried at low temperatures—preserving enzyme activity
- No fillers or binders—full organ spectrum in each serving
Conclusion
Fertility is a multifaceted journey requiring nutritional adequacy, metabolic balance, and oxidative support. Scientific evidence verifies the potency of folic acid, vitamin D, CoQ10, omega-3s, vitamins C/E, zinc, and inositol in enhancing gamete quality, hormone health, and reproductive outcomes.
Nutriest’s organ-based supplements elevate fertility support by offering naturally complex, bioavailable nutrients that complement these key supplements. Whether you’re trying to get pregnant, prepare for a healthy pregnancy, or simply support your reproductive system, integrating organ extracts with evidence-backed micronutrients may provide a holistic and scientifically aligned approach.
Take control of your fertility with nutrient-rich support from Nutriest’s organ-based formulas.
About the author:
Dr. Juan Carlos Cassano is a Medical Scientist, Clinical Chemist, and seasoned Project Manager with over 25 years of experience in pharmaceutical and clinical research. He specializes in the development, evaluation, and validation of medical assays, processes, and devices—ranging from AI flow cytometry to nanomedicine. His project leadership includes work on COVID-19 immune response, cancer screening (4DLifetest™), and drug delivery systems with Vifor Pharma. Dr. Cassano holds a PhD in Biochemistry and is the holder of U.S. Patent 7,560,226 for a novel assay technique. He is also an active industry collaborator and writer at Golden Era Bookworm.\
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